Nucleosides and Analogues
Medchemexpress LLC BVDU 5′-triphosphate ammonium | 98.0% | 590.11 g/mol | C11H19BrN3O14P3 | 10mg
BVDU 5 -Triphosphate ammonium is an antivirus agent with 5 -Triphosphate label targeting viral DNA polymerase BVDU 5 -Triphosphate ammonium shows excellent selectivity against varicella-zoster virus (VZV) and herpes simplex virus type 1 (HSV-1) due to a specific phosphorylation by the virus-encoded thymidine kinase
Medchemexpress LLC Motesanib diphosphate | 857876-30-3 | MFCD12407403 | >98.0% | 569.44 | C22H29N5O9P2 | 50 MG
Motesanib diphosphate is the diphosphate salt of motesanib, an ATP-competitive small-molecule inhibitor of VEGF receptors used as a research reagent for kinase and signaling studies.
- ATP-competitive inhibitor of VEGFR1/2/3 with low-nanomolar potency.
- Diphosphate salt form improves aqueous solubility for in vitro applications.
- Molecular weight 569.44; formula C22H29N5O9P2.
- High solubility in DMSO (≥110 mg/mL) and moderate solubility in water (≈5 mg/mL with warming).
- Intended for research and analytical use; not for human or clinical use.
Apexbio Technology LLC LDE225 Diphosphate 1218778-77-8 5mg
LDE225 Diphosphate (CAS 1218778-77-8) is a highly potent and selective antagonist of the Smoothened (Smo) receptor a seven-transmembrane protein involved in the Hedgehog (Hh) signaling pathway LDE225 inhibits Smo with IC50 values of 1 3 nM for murine and 2 5 nM for human Smo resulting in suppression of Hh signaling This pathway is implicated in cellular differentiation proliferation and oncogenesis In vitro LDE225 selectively binds Smo inhibiting Hh-dependent tumor cell growth In vivo it demonstrates dose-dependent antitumor efficacy in medulloblastoma xenograft mouse models LDE225 continues to be explored as a research tool and therapeutic candidate in Hh pathway-driven malignancies
Chem-Impex International, Inc. 3'-Azido-3'-deoxythymidine | 30516-87-1 | MFCD00006536 | 1G
3'-Azido-3'-deoxythymidine, 30516-87-1, MFCD00006536, 1G
Sigma Aldrich Fine Chemicals Biosciences Guanosine 981G
Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid intestinal cells blood-brain barrier and in brain microvessels.
Medchemexpress LLC Uridine, 2'-deoxy-4-thio- | 5580-20-1 | MFCD00058457 | 99.8% | 244.27 g·mol⁻¹ | C9H12N2O4S | 5 MG
4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analog supplied as a light-yellow solid and used as a research reagent in studies of DNA synthesis, nucleoside metabolism, and antitumor mechanisms. It is characterized for biochemical and cell-based experiments and provided with supporting analytical data.
- High purity (99.8%) for research applications.
- Sulfur-substituted nucleoside for incorporation and metabolism studies.
- Stable solid form with recommended low-temperature storage.
- Well-characterized molecular properties (C9H12N2O4S; 244.27 g·mol⁻¹).
- Available in small quantities suitable for laboratory-scale experiments.
Medchemexpress LLC 4-thio-2'-deoxyuridine | 5580-20-1 | MFCD00058457 | 99.8% | 244.27 g/mol | C9H12N2O4S | 100 MG
4-Thio-2'-deoxyuridine is a sulfur-substituted deoxyuridine nucleoside analogue used in biochemical and nucleic acid research, including studies of nucleic acid chemistry and incorporation into oligonucleotides. It has molecular formula C9H12N2O4S, molecular weight 244.27 g/mol, and a reported purity of 99.78%.
- Sulfur-substituted deoxyuridine analogue useful for nucleic acid studies.
- High reported purity (99.8%), suitable for analytical and synthetic applications.
- Available in multiple pack sizes for research-scale work.
- Provided with certificate of analysis and safety data sheet for quality and handling.
- Offered in solid form and as 10 mM DMSO solution for convenient use.
Sigma Aldrich Fine Chemicals Biosciences Adenosine Quantification A
Adenosine is a purine nucleoside base which is the precursor of adenosine triphosphate or ATP and is utilized thoroughly throughout the entire body in general metabolism. Extracellular adenosine acts as a local modulator with a generally cytoprotective function in the body. Its effects on tissue protection and repair fall into four categories increasing the ratio of oxygen supply to demand protecting against ischaemic damage by cell conditioning triggering anti-inflammatory responses and the promotion of angiogenesis.
Sigma Aldrich Fine Chemicals Biosciences Adenosine Deaminase from b
Molecular weight 32.5-33 kDapI 4.85